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Rifaximin is an antibiotic used to treat bacterial infections in the intestines. It is commonly used to treat traveler's diarrhea and irritable bowel syndrome with diarrhea (IBS-D). Unlike most antibiotics, rifaximin is not absorbed into the bloodstream, which means it mainly targets the digestive system and does not affect other bacteria in the body.

Rifaximin works by inhibiting the growth and spread of harmful bacteria in the gut, while promoting the growth of healthy gut flora. This helps to restore balance in the digestive system and reduce symptoms such as diarrhea, bloating, and abdominal pain.

Some common side effects of rifaximin include headache, nausea, and stomach upset. It is important to take rifaximin exactly as prescribed and complete the full course of treatment, even if symptoms improve before finishing the medication.

Rifaximin may interact with other medications, so it is important to inform your doctor of all medications you are taking before starting treatment with rifaximin.